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Occupational Health News & Analysis  

FDA Grants CLIA Waiver to Lead Screening Test

[Posted 9/21/06] The U.S. Food and Drug Administration (FDA) recently approved the use of LeadCare II Blood Lead Test System, a simple and portable lead screening test system by ESA Biosciences of Chelmsford, MA, at more than 115,000 certified point-of-care locations nationwide, including healthcare clinics, mobile health units, and schools. The test, which can be used by children and adults, uses a finger stick or venous whole blood sample and can be completed in as little as three minutes. The rapid test result would allow collection of a second sample for further testing if needed right after the first test is done, thereby eliminating the need for a follow-up visit. Hopefully, greater access to the test will result in earlier detection of children and adults exposed to lead in their homes, school, or work.

FDA granted the manufacturer’s application to categorize the test as waived under the Clinical Laboratory Improvement Amendment (CLIA), which permits its distribution to nontraditional laboratory sites that have a CLIA-waiver certificate. A CLIA waiver is given if a test is proven to be simple, accurate, and reasonably free of harm. Without the waiver, a test will only be available at certain hospitals, private and public health laboratories, and other testing facilities with the capability of performing moderate- and high-complexity testing.

The product was evaluated by testing 516 blood samples over a two-month period at 11 sites. Results showed that nearly 98% of the values measured by the test instrument were within Occupational Safety and Health Administrations (OSHA) recommendations for blood lead proficiency testing. Confirmatory tests using another laboratory method is required for blood lead values above 10 milligrams per deciliter.

Related Links:
FDA Press Release

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